IQVIA CORE Diabetes Model Version 10
Dear CDM User,
We are very happy to announce the launch of version 10 of the IQVIA Core Diabetes Model.
This version of the model comes with several improvements:
- Time In Range is now available as an alternative to HbA1c changes
- The clinical data of CVD submodules (HF, MI, Stroke) has been updated with more recent evidence.
- HF submodule now includes HF rehospitalizations
- An additional type 1 diabetes cardiovascular risk equation
- Additional options with new parameters for indirect cost calculations
- As changes in weight are appreciated differently around the globe, region specific BMI related disutility approaches are now available.
The many updates done to the model and its inputs obliged us to start with a new empty database.
Please note that there are, at the moment no plans to decommission version 9.0 of the CDM.
With the kindest regards
The CDM team
CDMTeam@iqvia.com
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IQVIA CORE Diabetes Model Version 9.5 Plus
Dear CDM User,
We are very happy to announce the launch of version 9.5 Plus of the IQVIA Core Diabetes Model.
This version of the model comes with several improvements:
- UKPDS 90 progression equations for several risk factors have been included
- A new eGFR progression option has been added
- Lipid parameters (TC, HDL, LDL, and triglycerides) will now follow the same progression option over time
- Asian risk equations have been adapted so that HbA1c changes influence outcomes
- The CDM Clinical Default includes new data on progression of blood pressure and lipids in type 1 diabetes patients
- EDIC risk of cardiovascular disease predictions after 26 years has been updated using extrapolation
The many updates done to the model and its inputs obliged us to start with a new empty database. Therefore, 9.5 settings are made available in version 9.5Plus, except the simulations to facilitate the start of the use of this new version.
Please note that there are, at the moment no plans to decommission version 9.0 of the CDM.
With the kindest regards
The CDM team
CDMTeam@iqvia.com
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IQVIA CORE Diabetes Model Version 9.5
Dear Core Diabetes Model User,
We are very happy to announce the launch of version 9.5 of the IQVIA Core Diabetes Model.
This version of the model comes with several new features:
- An uploadable excel as an alternative to populating the different settings online, you may now complete the following modules in an excel template and upload it in a couple of seconds:
- Cohort
- Economics
- Treatment
- Management
- Mortality tables
- Updated default values for Clinical settings, available to all users
- New cardiovascular risk equations:
- Swedish National Diabetes Registry for type 1
- Four Asian risk equations in type 2
- An alternative Framingham equation
- Progression of physiological parameters based on Swedish National Diabetes Registry
- Simplified foot ulcer sub-model
- Updated renal disease progression parameters
- Replacement of lactic acidosis as adverse event by three placeholder treatment-specific adverse events
- Replacement of depression sub-model by a placeholder complication sub-model
- Possibility to relate hypoglycemic events to cardiovascular events and mortality
- An adherence module that links adherence to a drug below 100% with decreased treatment impact on HbA1c and BMI.
- BMI disutility applicable via static approach (with a single data input) or a polynomial function
- Relative risk reduction on cardiovascular and renal events, allowing model calibration for cardiovascular outcomes trials
The many updates done to the model and its inputs obliged us to start with a new empty database. Therefore, settings from version 9.0 cannot be migrated to version 9.5. However, with the uploadable excel this should not cause you any delays (to the contrary).
We hope you are as excited as we are about this new version of the IQVIA Core Diabetes Model, and we are happy to tell you more about all the changes and implications. For that, we are working on a reference manual for version 9.5 where all inputs will be documented.
Please note that there are at the moment no plans to decommission version 9.0 of the CDM. It should at least be available until the end of 2021.
With the kindest regards
The CDM team
CDMTeam@iqvia.com
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